Coronavirus

Canonical Genome View

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Recent Coronavirus Articles

2009 Nov 17
Cleavage of the SARS Coronavirus Spike Glycoprotein by Airway Proteases Enhances Virus Entry into Human Bronchial Epithelial Cells In Vitro.
Kam et al
PloS one
2009 Nov 13
Specific real-time reverse transcription-polymerase chain reaction for detection and quantitation of turkey coronavirus RNA in tissues and feces from turkeys infected with turkey coronavirus.
Chen et al
Journal of virological methods
2009 Nov 13
MicroRNome analysis unravels the molecular basis of SARS infection in bronchoalveolar stem cells.
Mallick et al
PloS one
2009 Oct 20
Serosurvey of selected viruses in captive giant pandas (Ailuropoda melanoleuca) in China.
Qin et al
Veterinary microbiology
2009 Oct
Identification of human cell line model of persistent SARS coronavirus infection and studies of the response to cytokines and chemokines.
To and
Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine
Organism Photo

Severe Acute Respiratory Syndrome (SARS) is an atypical pneumonia that was first seen in the Guangdong Province, People''s Republic of China in 2002. In early 2003, international travel contributed to spreading the disease to over 25 countries across five continents. A global effort coordinated by the World Health Organization was successful in identifying the etiologic agent of this epidemic as a new member of the coronavirus family, termed SARS coronavirus (SARS-CoV). The epidemic was successfully controlled in June, 2003 through the implementation of rigorous public health measures. The 2002-2003 outbreak resulted in 8096 cases of SARS with 774 deaths, for a case fatality rate of 9.6% (http://www.who.int/csr/sars/country).

The SARS-CoV genome is a positive-sense, single-stranded RNA of approximately 29,740 nt with 14 open reading frames and 9 transcription regulatory sequences (TRS).

Orthologs

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