Organism Photo

Image

Brucella abortus - coccobacillus prokaryote (bacterium). (Courtesy of Dennis Kunkel Microscopy, Inc.)

Pathogen and Disease

Brucellae are Gram-negative, facultative, intracellular bacteria that can infect many species of animals and man. Brucellosis is a bacterial disease of animals that can be transmitted to humans. The genus Brucella consists of at least six species, designated on the basis of host preference, antigenic and biochemical characteristics as Brucella melitensis (goats and sheep), Brucella abortus (cattle), Brucella suis (pigs), Brucella canis (dogs), Brucella ovis (sheep) and Brucella neotomae (wood rats). B. abortus, B. melitensis and B. suis can all infect humans with similar serious disease consequences. Recently, Brucella spp. have been isolated from marine mammals and are infectious for humans Since brucellosis threatens the food supply and causes undulant fever, a long, debilitating disease in humans, Brucella species are recognized as potential agricultural, civilian, and military bioterrorism agents.

Treatment and Control

Brucellosis in food animals is controlled by vaccination. Human brucellosis is treatable with antibiotics, though the course of antibiotic treatment must be prolonged due to the intracellular nature of Brucella.

For references and expanded information, please refer to the B. melitensis PathInfo document.

Genomes (9) View Accession Type Size (bp)
Brucella abortus bv. 1 str. 9-941 Genome Browser Feature Table Experiments Summary NC_006932 chromosome 2124241
NC_006933 chromosome 1162204
Brucella abortus S19 Genome Browser Feature Table Experiments Summary NC_010742 chromosome 2122487
NC_010740 chromosome 1161449
Brucella canis ATCC 23365 Genome Browser Feature Table Experiments Summary NC_010103 chromosome 2105969
NC_010104 chromosome 1206800
Brucella melitensis ATCC 23457 Genome Browser Feature Table Experiments Summary VBI_000009 chromosome 2125701
VBI_000010 chromosome 1185518
Brucella suis ATCC 23445 Genome Browser Feature Table Experiments Summary NC_010169 chromosome 1923763
NC_010167 chromosome 1400844
Brucella suis 1330PATRIC Reference Genome Genome Browser Feature Table Experiments Summary NC_004310 chromosome 2107794
NC_004311 chromosome 1207381
Brucella melitensis 16M Genome Browser Feature Table Experiments Summary NC_003317 chromosome 2117144
NC_003318 chromosome 1177787
Brucella melitensis biovar Abortus 2308 Genome Browser Feature Table Experiments Summary NC_007618 chromosome 2121359
NC_007624 chromosome 1156948
Brucella ovis ATCC 25840 Genome Browser Feature Table Experiments Summary NC_009505 chromosome 2111370
NC_009504 chromosome 1164220

Unclosed Genomes

Genome name Number of contigs/scaffolds
Brucella ceti 7
Brucella str. BO1 55
Brucella abortus 2308 isolate A 9
Brucella str. BO2 196

Unclosed Genomes related to Brucella

Genome name Number of contigs
Ochrobactrum intermedium 4

Orthologs

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